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Symbol
Name
ID
Tgfbr2
transforming growth factor, beta receptor II
MGI:98729
Phenotype annotations related to liver/biliary system
Darker colors indicate more annotations
Human Phenotypes
Hepatosplenomegaly
Extrahepatic cholestasis
Jaundice
Neoplasm of the liver
Hepatocellular carcinoma
Disease(s) Associated with TGFBR2
Lynch syndrome
pancreatic cancer

Mouse Phenotypes
increased hepatocyte proliferation
liver inflammation
abnormal liver morphology
small liver
Availability Mouse Genotype
Tgfbr2em1(IMPC)Rbrc/Tgfbr2+
Tgfbr2tm1Sjkm/Tgfbr2+
Tgfbr2tm1.2Hlm/Tgfbr2tm1.2Hlm
Tg(Cd4-cre)1Cwi/0  (conditional)
Tgfbr2tm1Karl/Tgfbr2tm1Karl
Tg(Mx1-cre)1Cgn/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory